ea0073oc11.1 | Oral Communications 11: Adrenal and Cardiovascular Endocrinoloyg | ECE2021
Smith Gabrielle
, Lippert Juliane
, Altieri Barbara
, Elhassan Yasir
, Laura-Sophie Landwehr
, Prete Alessandro
, Appenzeller Silke
, Chortis Vasileios
, Steinhauer Sonja
, Asia Miriam
, Sutcliffe Robert
, Whalley Celina
, Arlt Wiebke
, Fassnacht Martin
, Ronchi Cristina
BackgroundAdrenocortical Carcinoma (ACC) is a rare aggressive cancer with a heterogeneous behaviour. Disease surveillance relies on frequent imaging, which has limited sensitivity and results in significant radiation exposure. Aim of the study was to investigate the role of circulating cell-free DNA (ccfDNA) as a biomarker for prognostication and disease monitoring in ACC.MethodsccfDNA was extracted from 1...