Searchable abstracts of presentations at key conferences in endocrinology

ea0073oc11.1 | Oral Communications 11: Adrenal and Cardiovascular Endocrinoloyg | ECE2021

Circulating cell-free DNA for prognostication and disease surveillance in adrenocortical carcinoma

Smith Gabrielle , Lippert Juliane , Altieri Barbara , Elhassan Yasir , Laura-Sophie Landwehr , Prete Alessandro , Appenzeller Silke , Chortis Vasileios , Steinhauer Sonja , Asia Miriam , Sutcliffe Robert , Whalley Celina , Arlt Wiebke , Fassnacht Martin , Ronchi Cristina

BackgroundAdrenocortical Carcinoma (ACC) is a rare aggressive cancer with a heterogeneous behaviour. Disease surveillance relies on frequent imaging, which has limited sensitivity and results in significant radiation exposure. Aim of the study was to investigate the role of circulating cell-free DNA (ccfDNA) as a biomarker for prognostication and disease monitoring in ACC.MethodsccfDNA was extracted from 1&#8...